Frequently Asked Questions


How are treatment sessions structured?

To ensure the effectiveness of the treatment and to adapt to the individual needs of each patient, sessions are scheduled on a personalized basis. Generally, it is recommended to start with a cycle of 10 sessions, distributed twice a week for a period of 4 to 5 weeks. This frequency allows for an optimal approach to chronic pathologies, ensuring intensive intervention at the beginning.

What happens in the early stages of treatment?

In the initial phase, especially for chronic conditions, it is common to start with a frequency of 3 to 4 sessions during the first week. This intensive approach aims to maximize therapeutic benefits from the outset. Subsequently, the frequency is adjusted to 2 sessions per week, based on the patient's response to treatment.

How is continuation of treatment decided after the first 10 sessions?

After completing the first course of treatment, a detailed reassessment is carried out to measure progress. This evaluation considers the goals previously established in collaboration with the patient. Depending on the results and the goals achieved, it may be decided to continue with the treatment at the same frequency or to space the sessions further apart, either every two weeks or once a month.

What is the long-term approach to treatment?

Treatment is adjusted on an ongoing basis, in close collaboration between the patient and the healthcare professional, to meet the established therapeutic goals. Flexibility in the scheduling of sessions allows the treatment to be adapted to the patient's evolution, ensuring that each step is taken in an informed manner and focused on the patient's well-being.

This personalized and adaptive approach ensures that treatment not only addresses symptoms effectively but also promotes a sustainable improvement in the patient's quality of life, adjusting to their needs and progress over time.

Does NESA® Non-Invasive Neuromodulation achieve 100% effectiveness in treating all pathologies of the autonomic nervous system it addresses?

As with any therapy, there is no universal solution with 100% effectiveness for all conditions. However, when clear guidelines are established based on sound clinical reasoning, accurate diagnosis, patient proactivity, detailed medical history, and scientifically validated assessments, NESA® Non-Invasive Neuromodulation demonstrates a high success rate. This success is observed in the treatment of conditions such as neuropathic pain, improvement of sleep quality, reduction of stress and anxiety, reduction of fatigue, and management of overactive bladder, provided that an adequate duration of treatment and number of sessions is adhered to, with a minimum of 10 sessions recommended.

Updated literature on the effectiveness of neuromodulation therapies includes:

"Changing Brain Networks Through Non-invasive Neuromodulation" - Frontiers in Human Neuroscience, 2018. This study highlights how non-invasive neuromodulation affects whole brain networks, offering promising prospects for treating various neurological and psychiatric disorders.

"Neuromodulation for chronic pain" - The Lancet, 2021. This review discusses neuromodulation as an expanding field for chronic pain treatment, including non-invasive techniques like transcranial magnetic stimulation and transcutaneous electrical stimulation.

"Non-invasive neuromodulation for migraine and cluster headache: a systematic review of clinical trials" - Journal of Neurology, Neurosurgery, and Psychiatry, 2019. This review compares different non-invasive neuromodulation techniques, demonstrating their safety and tolerability in treating migraine and cluster headaches.

"Non-invasive Neuromodulation in Primary Headaches" - Current Pain and Headache Reports, 2017. This article reviews the evidence base for non-invasive neuromodulation in primary headaches, emphasizing the therapeutic potential of these techniques.

"Cranial nerve non-invasive neuromodulation improves gait and balance in stroke survivors: A pilot randomised controlled trial" - Brain Stimulation, 2017. This pilot study demonstrates how non-invasive neuromodulation can enhance gait and balance in stroke survivors.

These studies and reviews underscore that while non-invasive neuromodulation does not guarantee 100% effectiveness in all cases, it represents a valuable therapeutic option with a high degree of success in various conditions, particularly when applied with a personalized and evidence-based approach.

What is the recommended interval between treatment sessions?

The scheduling of treatment sessions varies according to the specific needs of each patient and the nature of their condition. In a clinical setting, it is most common to allow a two-day interval between sessions, for example, scheduling appointments for Monday, Wednesday, and Friday, or Tuesday and Thursday. This frequency allows for an optimal balance between treatment and patient recovery time.

Is it possible to have daily treatment sessions?

Yes, it is possible to schedule daily treatment sessions, as long as one day of rest per week is included. This intensity may be appropriate for certain conditions or to accelerate results in specific phases of treatment.

What approach is recommended for chronic dysfunctions?

In cases of chronic dysfunction, a more intensive approach may be recommended at the beginning of treatment, such as four consecutive sessions. This approach aims to maximize the initial therapeutic impact and start the improvement process early in the treatment process.

Are there special considerations for the treatment of minors?

Yes, for children under 14 years of age, it is recommended to adjust the duration of sessions to a maximum of 30-45 minutes. This consideration considers the tolerance and attention span of the youngest children, ensuring that the treatment is effective and comfortable for them.


The planning of treatment sessions should be personalized, considering the patient's specific condition, response to treatment, and any needs. Flexibility in scheduling allows treatment to be adapted to the patient's progress, maximizing benefits, and promoting effective recovery. In all cases, it is essential to follow the recommendations of the healthcare professional to ensure the best possible results.

Yes, neuromodulation can indeed be used in amputee patients to alleviate a variety of symptoms and improve quality of life. To ensure the effectiveness of the treatment and to adapt it to the specific needs of these patients, special adapters designed for use in amputees are available.

Important Considerations:

Essential connection: It is crucial that the neuromodulation device is properly connected across the patient's limbs, including the use of amputee-specific adapters. Without this proper connection, the treatment will not generate the desired therapeutic effects.

Adapters for amputee patients: These adapters are designed to facilitate the correct application of neuromodulation therapy, ensuring that the electrical impulses reach the target areas effectively, even in the absence of one or more limbs.

Benefits of Neuromodulation for amputee patients:

Neuromodulation offers several potential benefits for amputee patients, including the reduction of phantom pain and improvement in overall sense of well-being. Personalization of treatment and the use of appropriate adapters are key to achieving these results.


The inclusion of neuromodulation in the treatment plan for amputee patients represents a valuable option capable of providing relief and improving quality of life. The correct use of specific adapters is essential to ensure the effectiveness of the treatment, underlining the importance of a personalized and technically sound approach to the care of these patients. As always, supervision by a qualified healthcare professional is essential to ensure the safety and efficacy of the treatment.

It can be used for a maximum of 10 hours a day.

Can NESA® neuromodulation be combined with therapeutic exercise or during a rehabilitation process?

Yes, it is entirely possible and recommended to integrate NESA® neuromodulation with therapeutic exercises or physical rehabilitation processes. This combination enhances the benefits of both treatments, allowing for a more efficient recovery adapted to the specific needs of the patient.

Key aspects of successful integration:

Cable management: To ensure a comfortable and effective experience during exercise or retraining, it is essential to properly manage the cabling of the NESA® device. This is achieved by placing the technology inside the NESA® backpack, with the cabling passing discreetly inside, avoiding interference or disturbance during activity.

Flexibility and mobility: The correct placement of the device and cabling allows the patient to move freely, performing a wide range of therapeutic exercises without restrictions, maximizing the benefits of the combined treatment.

Benefits of the combination:

Therapeutic synergy: The simultaneous use of neuromodulation with specific physical activities creates a synergy that can accelerate the recovery process, improve treatment efficacy, and strengthen long-term results.

Adaptability: This flexible approach demonstrates the adaptability of NESA® neuromodulation to different therapeutic environments, allowing its integration into personalized and dynamic rehabilitation programs.


The combination of NESA® Non-Invasive Neuromodulation with therapeutic exercise or retraining processes represents an advanced strategy for patient recovery and wellness. Intelligent cable management and the careful integration of technology into physical activity ensure an optimized therapeutic experience, highlighting the versatility and efficacy of NESA® neuromodulation as an adjunct to physical rehabilitation treatments.

Chronic Pain:

Chronic pain, which persists beyond the normal course of an illness or for more than three months, can arise from a variety of medical conditions. Neuromodulation offers a non-invasive and effective solution, providing relief and improving the quality of life for patients suffering from this prolonged discomfort.

Neuropathic Pain:

Neuropathic pain, resulting from damage or dysfunction of the nervous system, is characterized by burning, stabbing, or electric shocks. Neuromodulation acts directly on the nervous system, helping to relieve these debilitating symptoms.

Chemical and Nociceptive Pain:

In addition to its efficacy in treating chronic and neuropathic pain, neuromodulation has also been shown to be useful in managing chemical and nociceptive pain. These types of pain, caused by the release of chemicals in response to tissue injury and the activation of pain receptors, respectively, can be effectively addressed, offering a complementary therapeutic option for patients seeking relief.


Chronic pain, sleep problems, and urinary incontinence.


Acute Post-Surgical Hip Pain


Central Sensitization Syndrome and sleep problems


Covid-19 Persistent Pain and fatigue


Polyneuropathy in 4-year-old child


Fibromyalgia and sleep problems


Neuropathic pain due to Herpes Zoster


Peripheral neuropathy and sleep problems


Insomnia and Südeck

We recommend viewing the FAQs in the clinical doubts area, where you can find examples of clinical reasoning for more clinical cases at the end of the section.

Yes, many elite athletes incorporate advanced medical technology into their daily routines to optimize their performance and well-being. This technology has become an indispensable component in enhancing sleep quality, aiding recovery from fatigue to attain peak performance, improving cardiac variability, and expediting recovery from musculoskeletal injuries, among other benefits.

Key benefits for elite athletes:

Improved Sleep Quality: Restful sleep is crucial for both physical and mental recovery, enabling athletes to perform at their highest level.

Fatigue Recovery: Medical technology helps reduce accumulated fatigue, ensuring that athletes can train and compete at the highest levels.

Peak performance: By optimizing physical and mental performance, athletes can reach and maintain their peak performance during important competitions.

Improved Cardiac Variability: This indicator of well-being and recovery of the autonomic nervous system is essential for managing stress, as reflected by biomarkers such as cortisol and amylase, and facilitating recovery.

Recovery from Musculoskeletal Injuries: Medical technology accelerates the injury recovery process, enabling a quicker and safer return to activity.


Elite sportsmen and women, example 1 (Futbol Club Valencia, Spain)


Elite sportswomen, example 2 (Alejandra Salazar, 3 times world paddle tennis champion)


Elite sportsmen and women, example 3 (Pablo Lima, 2 times world padel champion)


Elite sportsmen and women, example 4 (Jairo Noriega, European Flyweight Boxing Champion)


Elite sportsmen and women, example 5 (Sergio Canales, professional footballer)


Elite sportsmen and women, example 6 (Mario Román, world superenduro motorbike champion)

NESA® medical technology is widely adopted by a diverse range of health professionals, including doctors from various specialties, physiotherapists across all branches, psychologists, and other disciplines such as podiatrists, nurses, and speech therapists.

Testimonials from health professionals:

For those interested in gaining a deeper understanding of how NESA® medical technology is revolutionizing healthcare practices, we are providing access to a collection of over 900 interviews with healthcare professionals from around the world, all subtitled in English. These testimonials provide a comprehensive overview of the positive impacts of NESA® across various medical and therapeutic specialties.


Traumatologists, example 1: Dr. Jordi Puigdellívol, FC Barcelona, Spain


Traumatologists, example 2: Dr. Lluís Till, Chief Medical Officer, Benfica FC, Portugal


Neurologists, example 1: Dr. Juan Manuel Ceballos, Alminar clinic, Spain


Neurologists, example 2: Dr Teresa Paiva, Centro de Medicina do Sueño (CENC), Portugal


Neurosurgeon, example 1: Dr. Santiago Garfias, Hospital de Mallorca, Spain


Neuroanaesthesiologist, example 1: Dr. Ernesto Delgado, Medical Expert in Neuroanaesthesiology, CIMEG, Madrid, Spain


Urologists, example 1: Dr. David Vázquez, Head of Functional Urology Department, Hospital Puerta de Hierro, Spain.


Urologists, example 2: Dr. Carmen González, Head of Urology at Fundación Jiménez Díaz and Hospitales Quirón Salud, Spain.


Gynaecologists, example 1: Dr. Alicia Martin, gynaecologist Hospital Materno Infantil Las Palmas, Spain


Gynaecologists, example 1: Dr. Alicia Martin, Gynaecologists, example 2: Dr. Zurami Estrada Blanco, Head of Gynaecology, CIMEG clinic, Spain


Integrative doctor, example 1: Dr. Agne Díaz, Agne Díaz, neuropediatra, Directora médica clínica CIMMAneuropaediatrician, medical director of the CIMMA clinic.


Integrative medicine, example 2: Dr. Sánchez and Dr. Guerra. CEO Biomédica, Las Palmas GC, SpainCEO Biomédica, Las Palmas GC, Spain


Physiotherapist to top athletes, example 1: Joaquín Juan, CEO clinic TVA International Elite Sport


Physiotherapist to Top Sportsmen and Women, Example 2: Antonio Gaspar, head physiotherapist of the Portuguese national football team.


Pelvic Floor Physiotherapist, Example 1: Laia Blanco, CEO of RAP Clinic, Spain.


Pelvic Floor Physiotherapist, Example 2: Ketty Ruiz, CEO of Clinic Ketty Ruiz, Spain.


General Physiotherapist, Example 1: Diego Álvarez, CEO of DAR Clinic, Spain.


General Physiotherapist, Example 2: Raúl Hernández, Spain.

The cost of treatment sessions varies significantly based on several determining factors. These include the country of treatment, specific regions within that country where the technology is available, the nature of the professional service required (such as assessments and evaluations), the integration of various services associated with the treatment, the setting of the sessions, and the total number of sessions needed, among other factors.

To obtain an accurate estimate tailored to your specific clinical needs, we recommend contacting the most specialized clinic in your area of interest directly. The clinic's team of healthcare experts or the clinic's administration will likely be ready to provide a private consultation and guide you through their personalized services.

Recommended Questions to Ask:

  • What would the first assessment session entail? Is it included, or is it charged separately? Will there be clinical follow-up at baseline, during
  • , and at the end of the first 10 sessions?
  • If I have multiple pathologies, will you collaborate with me to agree on clinical targets?
  • Can I pay for the treatment voucher in instalments?
  • If I am satisfied with the improvement, can I continue with another 10 treatments at a discounted rate?

During therapeutic sessions, particularly those that involve microcurrents, it is crucial to minimize potential interferences that could impact the effectiveness of the treatment. Scientific studies indicate that electromagnetic waves emitted by mobile devices can disrupt critical medical equipment, including those used to record or monitor vital functions like electrocardiograms (Fernández-Chimeno & Silva, 2010; Periyasamy & Dhanasekaran, 2015). Although specific research on interference from mobile phones in microcurrent therapies is limited, it is prudent to avoid using mobile phones during sessions to ensure the highest treatment efficacy.

In addition, creating a relaxing environment is essential for enhancing therapeutic effects. Disconnecting from electronic devices, including mobile phones, helps foster such an environment, providing a calmer and more beneficial experience for the patient. Engaging in non-digital activities such as reading a book is recommended during this time.


Fernández-Chimeno, M., & Silva, F. (2010). Mobile phones electromagnetic interference in medical environments: A review. 2010 IEEE International Symposium on Electromagnetic Compatibility. DOI: 10.1109/ISEMC.2010.5711291

Periyasamy, M., & Dhanasekaran, R. (2015). Evaluation of Electromagnetic Interference between Critical Medical Devices and New Generation Cellular Phones. Journal of Microwave Power and Electromagnetic Energy. DOI: 10.1080/08327823.2015.11689905

During Applied Superficial Neuromodulation (NESA®) sessions, the correct transmission of low-frequency microcurrents through the skin is crucial. Metals in direct contact with the skin can alter electrical impedance, which is vital for the effectiveness of the treatment. Metals can change the skin’s electrical conductivity, distorting the signals emitted by the device and thereby reducing treatment efficacy.

To ensure effective microcurrent therapy, it is recommended to remove any jewelry or metallic devices in direct contact with the skin. This precaution allows for optimal transmission of the microcurrents, facilitating the desired therapeutic effects without interference. However, if some metallic items cannot be removed, it is not necessarily decisive for the overall success of the therapy.


"Effect of Pressure on Skin-Electrode Impedance in Wearable Biomedical Measurement Devices" (2018) por Bahareh Taji, A. Chan, y S. Shirmohammadi. DOI: 10.1109/TIM.2018.2806950

"Dynamic Impedance Model of the Skin-Electrode Interface for Transcutaneous Electrical Stimulation" (2015) por J. L. Vargas Luna, M. Krenn, Jorge Armando Cortés Ramírez, y W. Mayr." DOI: 10.1371/journal.pone.0125609

"Lennox, A., Shafer, J., Hatcher, M., Beil, J., & Funder, S. J. (2002). Pilot study of impedance-controlled microcurrent therapy for managing radiation-induced fibrosis in head-and-neck cancer patients" International Journal of Radiation Oncology, Biology, Physics, 54(1), 23-34. DOI: 10.1016/S0360-3016(02)02898-5


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